Both the spawning of Artifact Spots and the resulting item are predetermined by the game's [[Random Seed]]. However, the removal logic RNG is not seeded similarly<ref name="removal" /> and the result of the removal routine is not repeatable. As a result of the random removal, on the [[Artifact_Spot#Spawning_&_Removal_Exceptions|days where processing is run extra times]], the behavior the player will observe from artifact spot creation is also no longer reliable with regard to the [[Random Seed]]. Still, on normal days, assuming the player removes all existing artifact spots, artifact spot creation results become possible to determine in advance.
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For the effect of the Random Seed advanced option on Artifact Spots, see [[Random Seed]].